Cheap and Effective Weight Loss Medications: Are They For You?
- Feb 8
- 4 min read
Finding the right weight loss medication can be challenging, especially with many options carrying hefty price tags such as the injectables. However, cost-effective alternatives exist that may support your weight loss journey. In this post, we will explore these affordable medications, their benefits, however their availability may vary across countries. Let’s delve into some notable options that can help you achieve your health goals without breaking the bank.
Metformin - Underestimated Choice in Weight Loss
I had to start with this one! Metformin is often known for its diabetic success and role. However, there is a role in weight loss alongside combating insulin resistance. This medication is the cheapest out of this list if paying privately and if you're considered diabetic it should be covered by insurance. Although the overall weight loss is on average 5%, the over all benefits may be significant for individuals who are pre-diabetic and/or have other comorbidities such as PCOS.
Qysmia: The Power of Combination Therapy
One of the more affordable yet effective long-term options is Qysmia, which combines Phentermine and Topiramate. This combo drug can aid in 10-14% in weight loss.
Phentermine, also known as Adipex, on its own has been used for short-term weight loss. Traditionally, it’s prescribed for use of no longer than three months due to concerns about side effects with hypertension and others that are common with stimulant-type medications, but emerging research suggests some patients can use it safely for extended periods when properly monitored. Phentermine can elevate serotonin and dopamine levels, effectively reducing cravings. Statistics indicate that 62% of people using Phentermine experience significant weight loss after just 12 weeks. It is known to lose 5% of total weight loss alone.
Topiramate has its own credentials; it is primarily prescribed for migraine prophylaxis and seizure conditions (less commonly) but can enhance the weight reduction effects with Phentermine. Some places approved Topiramate independently as it has been shown that this is the main component of its success in weight loss.

Vyvanse for Binge Eating Disorder
In North America, Vyvanse (or Lisdexamfetamine) is uniquely distinguished as the only FDA-approved medication for treating Binge Eating Disorder (BED), a condition affecting approximately 2% to 3% of adults. While Vyvanse is traditionally used to treat ADHD, it has shown promise in regulating binge-eating patterns, which can lead to weight loss for some individuals. Details of its mechanism of action could be found here, where I explain the specifics of BED.
It is important to discuss with a healthcare provider how Vyvanse may integrate into your treatment plan, especially since it carries stimulant properties. Some users report a 5% weight reduction within several months of starting the medication, making it an appealing option for those who face challenges with binge eating and weight management. Insurance may be able to cover this medication due to its FDA approval for both BED and ADHD.
Contrave: A Unique Combination
Another noteworthy medication is Contrave, which merges Bupropion and Naltrexone. This may be the most expensive out of this list if not covered by insurance. Bupropion is often prescribed for depression and smoking cessation, while Naltrexone is commonly used to treat alcohol dependence.
Contrave's dual-action mechanism targets both the psychological barriers to eating and the physical aspects of weight gain. Research shows that patients taking Contrave can expect to lose an average of 5-10% of their baseline weight over the span of a year. Nevertheless, individuals with a history of opioid use should take special care and talk with their healthcare provider about possible risks associated with Naltrexone.

When to Choose Medication
Deciding to use weight loss medication should be based on an extensive assessment by a healthcare provider. Key factors include your health history, existing medications, and personal weight loss goals. Dubbed the "5 As" approach — Ask, Assess, Advise, Agree, and Assist — this method promotes open communication between patients and providers.
Feeling empowered to discuss your concerns is crucial. Understanding any potential side effects or interactions can lead to healthier decisions regarding medication use in your overall weight management strategy.
Taking Charge of Your Weight Loss Journey
Cost-effective weight loss medications like Metformin, Qysmia, Vyvanse, and Contrave provide various options for those seeking assistance in their weight loss journey. Although these medications are not a magic bullet, they can be an integral part of a broader health plan that includes other comorbidities
Before trying any medication, always consult your healthcare provider about the options available to you, their potential effectiveness, and how they fit into your overall strategy. Prioritizing your well-being will guide you toward making informed choices. Stay informed about your options, and work closely with your provider for a healthier, happier you. Ultimately, it is not just about the numbers on a scale; it’s about improving your well-being and enjoying life to the fullest. Happy researching!
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